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While cagrilintide primarily modulates appetite through amylin pathways, retatrutide engages multiple incretin and metabolic hormone systems simultaneously [8]
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Several studies have demonstrated that silencing fat mass and obesity-associated protein (FTO) and iron regulatory protein 2 (IRP2) mitigates abnormalities in the amino acid antioxidant system and ferroptosis, thereby attenuating dopaminergic neuronal damage
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